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Comment
. 2017 Jun 13;135(24):e1135-e1136.
doi: 10.1161/CIRCULATIONAHA.117.027071.

Letter by Stamler et al Regarding Article, "Nitrite and S-Nitrosohemoglobin Exchange Across the Human Cerebral and Femoral Circulation: Relationship to Basal and Exercise Blood Flow Responses to Hypoxia"

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Comment

Letter by Stamler et al Regarding Article, "Nitrite and S-Nitrosohemoglobin Exchange Across the Human Cerebral and Femoral Circulation: Relationship to Basal and Exercise Blood Flow Responses to Hypoxia"

Jonathan S Stamler et al. Circulation. .
No abstract available

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Conflict of interest statement

Disclosures: Dr. Stamler has a financial interest in Nivalis Therapeutics, Adamas Pharma and LifeHealth. Dr. Reynolds has a financial interest in Miach Medical Innovations. Drs. Stamler and Reynolds also hold patents in this area that have been licensed for commercial development.

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References

    1. Bailey DM, Rasmussen P, Overgaard M, Evans KA, Bohm AM, Seifert T, Brassard P, Zaar M, Nielsen HB, Raven P, Secher NH. Nitrite and S-nitrosohemoglobin exchange across the human cerebral and femoral circulation; relationship to basal and exercise blood flow responses to hypoxia. Circulation. 2016 CIRCULATIONAHA.116.024226. - PubMed
    1. Singel DJ, Stamler JS. Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin. Annu Rev Physiol. 2005;67:99–145. - PubMed
    1. Zhang R, Hess DT, Qian Z, Hausladen A, Fonseca F, Chaube R, Reynolds JD, Stamler JS. Hemoglobin βCys93 is essential for cardiovascular function and integrated response to hypoxia. Proc Natl Acad Sci U S A. 2015;112:6425–6430. - PMC - PubMed
    1. Salgado MT, Ramasamy S, Tsuneshige A, Manoharan PT, Rifkind JM. A new paramagnetic intermediate formed during the reaction of nitrite with deoxyhemoglobin. J Am Chem Soc. 2011;133:13010–13022. - PMC - PubMed
    1. Hausladen A, Rafikov R, Angelo M, Singel DJ, Nudler E, Stamler JS. Assessment of nitric oxide signals by triiodide chemiluminescence. Proc Natl Acad Sci U S A. 2007;104:2157–2162. - PMC - PubMed