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Editorial
. 2017 May 26:4:45.
doi: 10.21037/sci.2017.04.08. eCollection 2017.

The mammary stem cell field wakes up to hibernating cells

Ewa M Michalak  1   2   3
Affiliations
Editorial

The mammary stem cell field wakes up to hibernating cells

Ewa M Michalak. Stem Cell Investig. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Proposed model of the mouse mammary epithelial cell hierarchy. Fetal mammary stem cells (MaSC) seed the postnatal MaSC compartment, which consists of a quiescent subset that favours self-renewal over proliferation. Bcl11bhigh cells (2), Lgr5+Tspan8hi (12) and embryonically derived long label-retaining cells (eLLRCs) (13) have all been reported to contribute to the quiescent stem cell pool, but their precise origin along the hierarchy and overlap with one another remains unclear (indicated by dashed lines). Cai and colleagues have recently shown that Bcl11bhigh cells are distinct from Procr+ multipotent progenitors (11), which may lie upstream of more committed luminal and myoepithelial progenitors. Adapted from (1).
See this image and copyright information in PMC

Comment on

References

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