doi: 10.1016/0006-291x(85)91401-9.
Effect of somatostatin on the proliferation of mouse spleen lymphocytes in vitro
- PMID: 2860904
- DOI: 10.1016/0006-291x(85)91401-9
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Effect of somatostatin on the proliferation of mouse spleen lymphocytes in vitro
Biochem Biophys Res Commun.
.
Abstract
The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated in vitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10(-7) M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.
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