NAFLD: PNPLA3 and obesity: a synergistic relationship in NAFLD

Affiliations

¹ Metabolic Research Laboratories, Level 4, Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Box 289, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK; and at the Department of Paediatrics, University of Cambridge, Box 116, Level 8, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
² Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, 4th Floor, William Leech Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK; and at the Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne NE7 7DN, UK.

Comment

Jake P Mann et al. Nat Rev Gastroenterol Hepatol. 2017 Sep.

. 2017 Sep;14(9):506-507.

doi: 10.1038/nrgastro.2017.74. Epub 2017 Jun 14.

¹ Metabolic Research Laboratories, Level 4, Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Box 289, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK; and at the Department of Paediatrics, University of Cambridge, Box 116, Level 8, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
² Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, 4th Floor, William Leech Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK; and at the Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne NE7 7DN, UK.

No abstract available

Comment on

Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci.
Stender S, Kozlitina J, Nordestgaard BG, Tybjærg-Hansen A, Hobbs HH, Cohen JC. Stender S, et al. Nat Genet. 2017 Jun;49(6):842-847. doi: 10.1038/ng.3855. Epub 2017 Apr 24. Nat Genet. 2017. PMID: 28436986 Free PMC article.