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Review
. 2017 Jun;58(Suppl 1):S38-S45.
doi: 10.4111/icu.2017.58.S1.S38. Epub 2017 Jun 2.

Endoscopic injection therapy

Sang Woon Kim  1 , Yong Seung Lee  1 , Sang Won Han  1
Affiliations
Review

Endoscopic injection therapy

Sang Woon Kim et al. Investig Clin Urol. 2017 Jun.

Abstract

Since the U.S. Food and Drug Administration approved dextranomer/hyaluronic acid copolymer (Deflux) for the treatment of vesicoureteral reflux, endoscopic injection therapy using Deflux has become a popular alternative to open surgery and continuous antibiotic prophylaxis. Endoscopic correction with Deflux is minimally invasive, well tolerated, and provides cure rates approaching those of open surgery (i.e., approximately 80% in several studies). However, in recent years a less stringent approach to evaluating urinary tract infections (UTIs) and concerns about long-term efficacy and complications associated with endoscopic injection have limited the use of this therapy. In addition, there is little evidence supporting the efficacy of endoscopic injection therapy in preventing UTIs and vesicoureteral reflux-related renal scarring. In this report, we reviewed the current literature regarding endoscopic injection therapy and provided an updated overview of this topic.

Keywords: Endoscopy; Injections; Vesicoureteral reflux.

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Conflict of interest statement

CONFLICTS OF INTEREST: The authors have nothing to disclose.

References

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