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Book

Peripheral Arterial Disease

Michael R. Zemaitis, Julia M. Boll  1 , Morgan Kato  2 , Maheswara Satya G. Golla  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Peripheral Arterial Disease

Michael R. Zemaitis et al.
Free Books & Documents

Excerpt

Peripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis that affects over 200 million people worldwide, particularly older adults and those with diabetes, smoking history, or chronic kidney disease. This condition results from progressive arterial narrowing, most often in the aortoiliac, femoropopliteal, and infrapopliteal segments, leading to reduced or impaired blood flow to the lower extremities.

PAD presents along a spectrum, from asymptomatic disease to intermittent claudication and chronic limb-threatening ischemia (CLTI). While many patients remain stable, a subset progresses to CLTI, which carries high risks of limb loss and mortality if not promptly treated. Interprofessional management enhances outcomes by preventing complications and addressing systemic cardiovascular risk factors.

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Conflict of interest statement

Disclosure: Michael Zemaitis declares no relevant financial relationships with ineligible companies.

Disclosure: Julia Boll declares no relevant financial relationships with ineligible companies.

Disclosure: Morgan Kato declares no relevant financial relationships with ineligible companies.

Disclosure: Maheswara Satya Golla declares no relevant financial relationships with ineligible companies.

References

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