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Book

Cocaine

John R. Richards, Erik G. Laurin
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Free Books & Documents
Book

Cocaine

John R. Richards et al.
Free Books & Documents

Excerpt

Cocaine hydrochloride topical solution contains 4% cocaine. It is not FDA-approved but allowed for only the following indications: topical anesthesia of the mucous membranes of the oral, laryngeal, and nasal cavities. Its vasoconstrictive properties also make it useful for the temporary treatment of epistaxis before cauterization or packing, which is considered off-label use. This activity reviews the mechanism of action, adverse event profile, toxicity, dosing, pharmacodynamics, and monitoring of cocaine pertinent for interprofessional team members when used as indicated in the clinical setting.

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Conflict of interest statement

Disclosure: John Richards declares no relevant financial relationships with ineligible companies.

Disclosure: Erik Laurin declares no relevant financial relationships with ineligible companies.

References

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