Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Atorvastatin

Lindsey A. McIver  1 , Momin S. Siddique  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Atorvastatin

Lindsey A. McIver et al.
Free Books & Documents

Excerpt

HMG-CoA reductase inhibitors (statins) are lipid-lowering medications used in the primary, secondary, and tertiary prevention of coronary heart disease. Atorvastatin is a medication primarily used to manage and treat dyslipidemias and prevent cardiovascular disease. This activity focuses on the indications, mechanism of action, and contraindications of atorvastatin as a valuable agent in managing these conditions. The activity reviews the warnings, adverse event profile, toxicity, and key considerations, including monitoring and relevant drug interactions. Understanding the intricate pharmacology of atorvastatin enables healthcare professionals to tailor treatment plans to individual patient needs. Notably, the emphasis lies on empowering healthcare professionals, highlighting the essential role of the interprofessional healthcare team in managing atorvastatin therapy for hyperlipidemia and reducing cardiovascular risk.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Lindsey McIver declares no relevant financial relationships with ineligible companies.

Disclosure: Momin Siddique declares no relevant financial relationships with ineligible companies.

References

    1. Raddino R, Della Pina P, Gorga E, Caretta G, Madureri A, Dei Cas L. [Indications for statin therapy in patients with acute coronary syndrome of ischemic origin]. G Ital Cardiol (Rome) 2010 Oct;11(10 Suppl 1):78S-83S. - PubMed
    1. Jacobson TA, Ito MK, Maki KC, Orringer CE, Bays HE, Jones PH, McKenney JM, Grundy SM, Gill EA, Wild RA, Wilson DP, Brown WV. National lipid association recommendations for patient-centered management of dyslipidemia: part 1--full report. J Clin Lipidol. 2015 Mar-Apr;9(2):129-69. - PubMed
    1. Jacobson TA, Maki KC, Orringer CE, Jones PH, Kris-Etherton P, Sikand G, La Forge R, Daniels SR, Wilson DP, Morris PB, Wild RA, Grundy SM, Daviglus M, Ferdinand KC, Vijayaraghavan K, Deedwania PC, Aberg JA, Liao KP, McKenney JM, Ross JL, Braun LT, Ito MK, Bays HE, Brown WV, Underberg JA, NLA Expert Panel National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2. J Clin Lipidol. 2015 Nov-Dec;9(6 Suppl):S1-122.e1. - PubMed
    1. Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC, Sperling L, Virani SS, Yeboah J. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019 Jun 18;139(25):e1082-e1143. - PMC - PubMed
    1. Writing Committee Members. Virani SS, Newby LK, Arnold SV, Bittner V, Brewer LC, Demeter SH, Dixon DL, Fearon WF, Hess B, Johnson HM, Kazi DS, Kolte D, Kumbhani DJ, LoFaso J, Mahtta D, Mark DB, Minissian M, Navar AM, Patel AR, Piano MR, Rodriguez F, Talbot AW, Taqueti VR, Thomas RJ, van Diepen S, Wiggins B, Williams MS. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2023 Aug 29;82(9):833-955. - PubMed

Publication types

LinkOut - more resources