Plaque Psoriasis

Excerpt

Plaque psoriasis, also known as psoriasis vulgaris, is a chronic, immune-mediated inflammatory skin disorder characterized by well-demarcated, erythematous plaques covered with silvery-white scales (see Image. Plaque Psoriasis: Multiple Erythematous Scaly Plaques Over the Back). Plaque psoriasis is the most prevalent form of psoriasis, accounting for approximately 80% to 90% of all psoriasis cases. This disorder is typically a lifelong relapsing-remitting condition, with flares often triggered by infections, stress, medications, or trauma. Some patients may experience stable disease with minimal symptoms, whereas others develop severe, widespread plaques that significantly impair their quality of life.

Plaque psoriasis most commonly affects the extensor surfaces of the elbows and knees, the scalp, the trunk, and the lumbosacral region; it can also appear on the nails and intertriginous areas. In some cases, it may progress to involve the joints, manifesting as psoriatic arthritis, or be associated with systemic inflammatory comorbidities such as metabolic syndrome, cardiovascular disease, and depression. Early recognition and comprehensive management are crucial to mitigate disease burden and long-term complications.