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Book

Dawn Phenomenon

Teri B. O'Neal  1 , Euil E. Luther  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Dawn Phenomenon

Teri B. O'Neal et al.
Free Books & Documents

Excerpt

The “dawn phenomenon” refers to periodic episodes of hyperglycemia occurring in the early morning hours. Originally described in the early 1980s by Schmidt et al., the dawn phenomenon differs from the Somogyi effect in that it is not preceded by an episode of hypoglycemia. Understanding and differentiating between these two clinical entities becomes critical in the optimal management of diabetes.

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Conflict of interest statement

Disclosure: Teri O'Neal declares no relevant financial relationships with ineligible companies.

Disclosure: Euil Luther declares no relevant financial relationships with ineligible companies.

References

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    1. Rybicka M, Krysiak R, Okopień B. The dawn phenomenon and the Somogyi effect - two phenomena of morning hyperglycaemia. Endokrynol Pol. 2011;62(3):276-84. - PubMed
    1. Boden G, Chen X, Urbain JL. Evidence for a circadian rhythm of insulin sensitivity in patients with NIDDM caused by cyclic changes in hepatic glucose production. Diabetes. 1996 Aug;45(8):1044-50. - PubMed
    1. Perriello G, Pampanelli S, Del Sindaco P, Lalli C, Ciofetta M, Volpi E, Santeusanio F, Brunetti P, Bolli GB. Evidence of increased systemic glucose production and gluconeogenesis in an early stage of NIDDM. Diabetes. 1997 Jun;46(6):1010-6. - PubMed
    1. Radziuk J, Pye S. Diurnal rhythm in endogenous glucose production is a major contributor to fasting hyperglycaemia in type 2 diabetes. Suprachiasmatic deficit or limit cycle behaviour? Diabetologia. 2006 Jul;49(7):1619-28. - PubMed

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