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Book

Tularemia

Jessica Snowden  1 , Kari A. Simonsen  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Tularemia

Jessica Snowden et al.
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Excerpt

Tularemia is an acute febrile zoonotic illness caused by the highly infectious Gram-negative organism Francisella tularensis. It is important to maintain a high degree of clinical suspicion for tularemia infections as symptoms can vary depending on the route of infection.

F. Tularensis is one of the most infectious agents known; as few as 10-25 organisms can cause an infection in humans. Several subspecies of the bacteria are known and their virulence and geographical range also vary. In the US, tularemia is rare with most cases reported in the southern and central states. However, over the years cases have been reported in the Northern part of the country.

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Conflict of interest statement

Disclosure: Jessica Snowden declares no relevant financial relationships with ineligible companies.

Disclosure: Kari Simonsen declares no relevant financial relationships with ineligible companies.

References

    1. Frischknecht M, Meier A, Mani B, Joerg L, Kim OC, Boggian K, Strahm C. Tularemia: an experience of 13 cases including a rare myocarditis in a referral center in Eastern Switzerland (Central Europe) and a review of the literature. Infection. 2019 Oct;47(5):683-695. - PubMed
    1. Kopping EJ, Doyle CR, Sampath V, Thanassi DG. Contributions of TolC Orthologs to Francisella tularensis Schu S4 Multidrug Resistance, Modulation of Host Cell Responses, and Virulence. Infect Immun. 2019 Apr;87(4) - PMC - PubMed
    1. Kervyn A, Le Guern A, Gillard M, Bataille M, Modiano P. [Tularemia: A case report]. Ann Dermatol Venereol. 2019 Feb;146(2):131-134. - PubMed
    1. Balestra A, Bytyci H, Guillod C, Braghetti A, Elzi L. A case of ulceroglandular tularemia presenting with lymphadenopathy and an ulcer on a linear morphoea lesion surrounded by erysipelas. Int Med Case Rep J. 2018;11:313-318. - PMC - PubMed
    1. Donate-Pérez-Molino P, Castelló-Abietar C, Fernández-Suárez J, de Vicente JC. Tularemia: diagnosis of an unexpected oculoglandular case in a non-endemic area by universal PCR. Enferm Infecc Microbiol Clin (Engl Ed) 2019 Nov;37(9):620-621. - PubMed

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