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Book

High Altitude Cerebral Edema

Jacob D. Jensen  1 , Andrew L. Vincent  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Free Books & Documents
Book

High Altitude Cerebral Edema

Jacob D. Jensen et al.
Free Books & Documents

Excerpt

High Altitude Cerebral Edema (HACE) is a severe and potentially fatal manifestation of high altitude illness and is often characterized by ataxia, fatigue, and altered mental status. HACE is often thought of as an extreme form/end-stage of Acute Mountain Sickness (AMS). Although HACE represents the least common form of altitude illness, it may progress rapidly to coma and death as a result of brain herniation within 24 hours, if not promptly diagnosed and treated.

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Conflict of interest statement

Disclosure: Jacob Jensen declares no relevant financial relationships with ineligible companies.

Disclosure: Andrew Vincent declares no relevant financial relationships with ineligible companies.

References

    1. Gonzalez Garay A, Molano Franco D, Nieto Estrada VH, Martí-Carvajal AJ, Arevalo-Rodriguez I. Interventions for preventing high altitude illness: Part 2. Less commonly-used drugs. Cochrane Database Syst Rev. 2018 Mar 12;3(3):CD012983. - PMC - PubMed
    1. Nieto Estrada VH, Molano Franco D, Medina RD, Gonzalez Garay AG, Martí-Carvajal AJ, Arevalo-Rodriguez I. Interventions for preventing high altitude illness: Part 1. Commonly-used classes of drugs. Cochrane Database Syst Rev. 2017 Jun 27;6(6):CD009761. - PMC - PubMed
    1. Jensen JD, Vincent AL. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Jul 17, High Altitude Cerebral Edema. - PubMed
    1. Khodaee M, Grothe HL, Seyfert JH, VanBaak K. Athletes at High Altitude. Sports Health. 2016 Mar-Apr;8(2):126-32. - PMC - PubMed
    1. Derby R, deWeber K. The athlete and high altitude. Curr Sports Med Rep. 2010 Mar-Apr;9(2):79-85. - PubMed

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