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Book

Acanthosis Nigricans

Evelyn K. Hughes  1 , Mark F. Brady  2 , Prashanth Rawla  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Acanthosis Nigricans

Evelyn K. Hughes et al.
Free Books & Documents

Excerpt

Acanthosis nigricans is a velvety, darkening of the skin that usually occurs in intertriginous areas. This hyperpigmentation has poorly defined borders, usually occurs in skin fold areas, such as the back of the neck, axilla, and groin, and may include thickening of the skin. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders and with the use of certain medications like systemic glucocorticoids and oral contraceptives.

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Conflict of interest statement

Disclosure: Evelyn Hughes declares no relevant financial relationships with ineligible companies.

Disclosure: Mark Brady declares no relevant financial relationships with ineligible companies.

Disclosure: Prashanth Rawla declares no relevant financial relationships with ineligible companies.

References

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