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Book

Colchicine

Nazia M. Sadiq, Kenneth J. Robinson  1 , Jamie M. Terrell  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Colchicine

Nazia M. Sadiq et al.
Free Books & Documents

Excerpt

Colchicine is FDA-approved for gout prevention, treatment of acute gouty flares, and familial Mediterranean fever. Off-label applications include hepatic cirrhosis, primary biliary cirrhosis, and pseudogout. The primary mechanism of action involves anti-inflammatory effects, which are central to managing these conditions. Understanding the pharmacodynamics, dosing, adverse event profile, and toxicity is essential for optimizing patient outcomes.

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Conflict of interest statement

Disclosure: Nazia Sadiq declares no relevant financial relationships with ineligible companies.

Disclosure: Kenneth Robinson declares no relevant financial relationships with ineligible companies.

Disclosure: Jamie Terrell declares no relevant financial relationships with ineligible companies.

References

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