Immunity at the forefront of the brain: A new genetic model of FTD
- PMID: 28615359
- DOI: 10.1126/scitranslmed.aan5227
Immunity at the forefront of the brain: A new genetic model of FTD
Abstract
Functional characterization of a genetic variant linked to frontotemporal dementia in a murine model reveals deficits in cerebral immune response and metabolism.
Copyright © 2017, American Association for the Advancement of Science.
Comment on
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The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.EMBO J. 2017 Jul 3;36(13):1837-1853. doi: 10.15252/embj.201796516. Epub 2017 May 30. EMBO J. 2017. PMID: 28559417 Free PMC article.
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