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Comment
. 2017 Jul 1;82(1):e1-e3.
doi: 10.1016/j.biopsych.2017.05.007.

The N-Methyl-D-Aspartate Receptor: Memory, Madness, and More

Alejandro Ramirez  1 , Melissa R Arbuckle  2
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Comment

The N-Methyl-D-Aspartate Receptor: Memory, Madness, and More

Alejandro Ramirez et al. Biol Psychiatry. .
No abstract available

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Figures

Figure 1
Figure 1
Structure of the N-methyl-D-aspartate (NMDA) receptor. On the left is a schematic of neuron A making synaptic contact with the dendrites of neuron B. Illustrated in the blue circles are NMDA receptors, demonstrating the distinct compartmental localization of somatic vs. dendritic NMDA receptors. Magnified on the right is the tetrameric structure of an NMDA receptor on the postsynaptic membrane of a synapse, along with the multiple agonists, co-agonists, and various targets for pharmacologic modulation. PCP, phencyclidine.
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References

    1. Cahalan S. Brain on Fire: My Month of Madness. New York: Simon and Schuster; 2013.
    1. Allen RM, Young SJ. Phencyclidine-induced psychosis. Am J Psychiatry. 1978;135:1081–1084. - PubMed
    1. Moghaddam B, Krystal JH. Capturing the angel in “angel dust”: Twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humans. Schizophr Bull. 2012;38:942–949. - PMC - PubMed
    1. Ramirez A, Arbuckle MR. Synaptic plasticity: The role of learning and unlearning in addiction and beyond. Biol Psychiatry. 2016;80:e73–e75. - PMC - PubMed
    1. Cull-Candy S, Brickley S, Farrant M. NMDA receptor subunits: Diversity, development and disease. Curr Opin Neurobiol. 2001;11:327–335. - PubMed

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