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Review
. 2017 Mar 8;8(1):17-22.
doi: 10.1007/s13167-017-0086-6. eCollection 2017 Mar.

Feeling cold and other underestimated symptoms in breast cancer: anecdotes or individual profiles for advanced patient stratification?

Olga Golubnitschaja  1   2
Affiliations
Review

Feeling cold and other underestimated symptoms in breast cancer: anecdotes or individual profiles for advanced patient stratification?

Olga Golubnitschaja. EPMA J. .

Abstract

Breast cancer (BC) epidemic is recognised as being characteristic for the early twenty-first century. BC is a multifactorial disease, and a spectrum of modifiable (preventable) factors significantly increasing risks has been described. This article highlights a series of underestimated symptoms for consequent BC risk assessment and patient stratification. Phenomena of the deficient thermoregulation, altered sensitivity to different stimuli (pain, thirst, smell, light, stress provocation), dehydration, altered circadian and sleep patterns, tendency towards headache, migraine attacks and dizziness, as well as local and systemic hypoxic effects are discussed for BC patients providing functional links and proposing new approaches in the overall BC management.

Keywords: Breast cancer; Endothelin; Flammer syndrome; Pain; Predictive preventive personalised medicine; Stress.

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Conflict of interest statement

Conflict of interest

The author declares that she has no conflict of interest.

Statement of informed consent

Patients have not been involved in the study.

Statement of human and animal rights

No experiments have been performed including patients and/or animals.

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