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Comparative Study
. 2017 Sep;47(9):2783-2794.
doi: 10.1007/s10803-017-3200-7.

A Prospective Study of the Concordance of DSM-IV and DSM-5 Diagnostic Criteria for Autism Spectrum Disorder

Micah O Mazurek  1   2 , Frances Lu  3 , Heather Symecko  3   4 , Eric Butter  5 , Nicole M Bing  6 , Rachel J Hundley  7 , Marie Poulsen  8 , Stephen M Kanne  9 , Eric A Macklin  3   10 , Benjamin L Handen  11
Affiliations
Comparative Study

A Prospective Study of the Concordance of DSM-IV and DSM-5 Diagnostic Criteria for Autism Spectrum Disorder

Micah O Mazurek et al. J Autism Dev Disord. 2017 Sep.

Abstract

The transition from DSM-IV to DSM-5 criteria for autism spectrum disorder (ASD) sparked considerable concern about the potential implications of these changes. This study was designed to address limitations of prior studies by prospectively examining the concordance of DSM-IV and final DSM-5 criteria on a consecutive sample of 439 children referred for autism diagnostic evaluations. Concordance and discordance were assessed using a consistent diagnostic battery. DSM-5 criteria demonstrated excellent overall specificity and good sensitivity relative to DSM-IV criteria. Sensitivity and specificity were strongest for children meeting DSM-IV criteria for autistic disorder, but poor for those meeting criteria for Asperger's disorder and pervasive developmental disorder. Higher IQ, older age, female sex, and less pronounced ASD symptoms were associated with greater discordance.

Keywords: Autism spectrum disorder; Concordance; DSM-5; Sensitivity; Specificity.

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References

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