Comment
doi: 10.1016/j.cell.2017.05.043.
Sex at Atomic Resolution
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- PMID: 28622504
- DOI: 10.1016/j.cell.2017.05.043
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Comment
Sex at Atomic Resolution
Cell.
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Abstract
Interspecies fertilization is rare, partly due to species separation enforced at the molecular level. In this issue, Raj et al. now reveal the crystal structures of mollusk egg coat protein, VERL, complexed with cognate sperm protein lysin. Given that VERL is structurally similar to mammalian ZP2, the mechanism elucidating species-specific gamete recognition likely exists in mammals.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Structural Basis of Egg Coat-Sperm Recognition at Fertilization.Cell. 2017 Jun 15;169(7):1315-1326.e17. doi: 10.1016/j.cell.2017.05.033. Cell. 2017. PMID: 28622512 Free PMC article.
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