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. 2017 Jul 13;35(32):3910-3912.
doi: 10.1016/j.vaccine.2017.06.004. Epub 2017 Jun 13.

ADE and dengue vaccination

Affiliations

ADE and dengue vaccination

Ruth Aralí Martínez-Vega et al. Vaccine. .

Abstract

The vaccine against Dengue virus (DENV), Dengvaxia® (CYD), produced by Sanofi-Pasteur, has been registered by several national regulatory agencies; nevertheless, the performance and security of this vaccine have been challenged in a series of recent papers. In this work, we intend to contribute to the debate by analyzing the concept of an enhancing vaccine, presenting objections to the epidemiological model base of the concept and, likewise, presenting data that contradict that concept.

Keywords: Dengue; Immunity; Pathogenesis; Vaccine.

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