ADE and dengue vaccination
- PMID: 28623027
- DOI: 10.1016/j.vaccine.2017.06.004
ADE and dengue vaccination
Abstract
The vaccine against Dengue virus (DENV), Dengvaxia® (CYD), produced by Sanofi-Pasteur, has been registered by several national regulatory agencies; nevertheless, the performance and security of this vaccine have been challenged in a series of recent papers. In this work, we intend to contribute to the debate by analyzing the concept of an enhancing vaccine, presenting objections to the epidemiological model base of the concept and, likewise, presenting data that contradict that concept.
Keywords: Dengue; Immunity; Pathogenesis; Vaccine.
Copyright © 2017 Elsevier Ltd. All rights reserved.
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