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Review
. 2017 Dec;19(12):1423-1429.
doi: 10.1007/s12094-017-1690-6. Epub 2017 Jun 16.

Pancreatic ductal adenocarcinoma: metastatic disease

A J Muñoz Martín  1 , J Adeva  2 , J Martínez-Galán  3 , J J Reina  4 , M Hidalgo  5
Affiliations
Review

Pancreatic ductal adenocarcinoma: metastatic disease

A J Muñoz Martín et al. Clin Transl Oncol. 2017 Dec.

Abstract

The treatment of choice of metastatic PADC is systemic chemotherapy. In the last decade, there have been significant advances in this area. New combination poli-chemotherapy schemes have shown a significant increase in overall survival and progression-free survival without impairing quality of life. In addition, the value of second-line chemotherapy treatment has consolidated and a new concept called "therapeutic sequencing" has also emerged. The aim of this article is to review the different therapeutic options in metastatic PDAC based on patient's characteristics.

Keywords: Management; Metastatic; Pancreatic ductal adenocarcinoma; Re-evaluation; Treatment sequencing.

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