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. 2017 Jun 8;22(6):911.
doi: 10.3390/molecules22060911.

Systematic Review of Chemical Constituents in the Genus Lycium (Solanaceae)

Dan Qian  1   2 , Yaxing Zhao  3 , Guang Yang  4 , Luqi Huang  5
Affiliations

Systematic Review of Chemical Constituents in the Genus Lycium (Solanaceae)

Dan Qian et al. Molecules. .

Abstract

The Lycium genus is widely used as a traditional Chinese medicine and functional food. Many of the chemical constituents of the genus Lycium were reported previously. In this review, in addition to the polysaccharides, we have enumerated 355 chemical constituents and nutrients, including 22 glycerogalactolipids, 29 phenylpropanoids, 10 coumarins, 13 lignans, 32 flavonoids, 37 amides, 72 alkaloids, four anthraquinones, 32 organic acids, 39 terpenoids, 57 sterols, steroids, and their derivatives, five peptides and three other constituents. This comprehensive study could lay the foundation for further research on the Lycium genus.

Keywords: Lycii cortex; Lycium genus; chemical constituents; goji berry.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Different subtype comparison of the 355 constituents reported from Lycium genus.
Figure 2
Figure 2
Chemical structures of compounds 18–22.
Figure 3
Figure 3
Chemical structures of compounds 23–25, 29–31.
Figure 4
Figure 4
Chemical structures of compounds 52–57, 61.
Figure 5
Figure 5
Chemical structures of compounds 63–64 and 68–74.
Figure 6
Figure 6
Chemical structures of compounds 81, 84, 88 and 94.
Figure 7
Figure 7
Chemical structures of compounds 99–106.
Figure 8
Figure 8
Chemical structures of compounds 107–143.
Figure 8
Figure 8
Chemical structures of compounds 107–143.
Figure 8
Figure 8
Chemical structures of compounds 107–143.
Figure 8
Figure 8
Chemical structures of compounds 107–143.
Figure 9
Figure 9
Chemical structures of compounds 144–157.
Figure 9
Figure 9
Chemical structures of compounds 144–157.
Figure 10
Figure 10
Chemical structures of compounds 158–163.
Figure 11
Figure 11
Chemical structures of compounds 164–167.
Figure 12
Figure 12
Chemical structures of compounds 168–184.
Figure 13
Figure 13
Chemical structures of compounds 185–188.
Figure 14
Figure 14
Chemical structures of compounds 194 and 195.
Figure 15
Figure 15
Chemical structures of compounds 201–203.
Figure 16
Figure 16
Chemical structures of compounds 204–215.
Figure 16
Figure 16
Chemical structures of compounds 204–215.
Figure 17
Figure 17
Chemical structures of compounds 216–219.
Figure 18
Figure 18
Chemical structures of compounds 220–251.
Figure 18
Figure 18
Chemical structures of compounds 220–251.
Figure 19
Figure 19
Chemical structures of compounds 252–263, 266.
Figure 20
Figure 20
Chemical structures of compounds 271 and 274.
Figure 21
Figure 21
Chemical structures of compounds 283–290.
Figure 21
Figure 21
Chemical structures of compounds 283–290.
Figure 22
Figure 22
Chemical structures of compounds 291–347.
Figure 22
Figure 22
Chemical structures of compounds 291–347.
Figure 22
Figure 22
Chemical structures of compounds 291–347.
Figure 22
Figure 22
Chemical structures of compounds 291–347.
Figure 23
Figure 23
Chemical structures of compounds 348–352.
Figure 24
Figure 24
Chemical structures of compounds 353–355.
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References

    1. Zhang Z.Y., Lu A.M., D‘Arcy W.G. Flora of China. Volume 17: Verbenaceae through Solanaceae. Science Press; Beijing, China: Missouri Botanical Garden Press; St. Louis, MO, USA: 1994. pp. 301–304.
    1. Chinese Pharmacopoeia Commission . Pharmacopoeia of the People’s Republic of China Part I. Chemical Industry Press; Beijing, China: 2015.
    1. Yuenshan H., Yu M.S., Suetyi Y., Kwokfai S., Waihung Y. Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons. Cell. Mol. Neurobiol. 2009;29:1233–1244. - PMC - PubMed
    1. Yu M.S., Wong Y.Y., So K.F., Fang J.N., Yuen W.H., Chang C.C. New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway. Brain Res. 2007;1153:221. doi: 10.1016/j.brainres.2007.03.074. - DOI - PubMed
    1. Bie M., Lv Y., Ren C., Xing F., Cui Q., Xiao J., So K.F. Lycium barbarum polysaccharide improves bipolar pulse current-induced microglia cell injury through modulating autophagy. Cell Trans. 2015;24:419–428. doi: 10.3727/096368915X687453. - DOI - PubMed

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