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. 2017 Aug 24;61(9):e01008-17.
doi: 10.1128/AAC.01008-17. Print 2017 Sep.

Ceftazidime-Avibactam and Aztreonam, an Interesting Strategy To Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae and Pseudomonas aeruginosa

Benjamin Davido  1 , Lesly Fellous  2 , Christine Lawrence  3   4 , Virginie Maxime  5 , Martin Rottman  4   6 , Aurélien Dinh  7
Affiliations

Ceftazidime-Avibactam and Aztreonam, an Interesting Strategy To Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae and Pseudomonas aeruginosa

Benjamin Davido et al. Antimicrob Agents Chemother. .
No abstract available

Keywords: avibactam; aztreonam; ceftazidime.

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Figures

FIG 1
FIG 1
Susceptibility testing showing with ellipsometry the effect of the synergistic combination of CAZ-AVI and ATM. The combination (middle strip) was tested by first applying an ATM strip to the Mueller-Hinton (MH) agar, removing it after 5 min, and then applying a CAZ-AVI strip on the exact same location and placing back the ATM strip to read the susceptibility to ATM in the presence of AVI (and CAZ). (Top panel) K. pneumoniae NDM-1/OXA-48 from patient 1. (Bottom panel) Pseudomonas aeruginosa NDM-1/AmpC from patient 2.
See this image and copyright information in PMC

References

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