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Editorial
. 2017 Aug;28(8):2258-2260.
doi: 10.1681/ASN.2017040470. Epub 2017 Jun 19.

Urine Ammonium and Preclinical Acidosis in CKD

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Editorial

Urine Ammonium and Preclinical Acidosis in CKD

Thomas D DuBose Jr. J Am Soc Nephrol. 2017 Aug.
No abstract available

Keywords: Cell Signaling; acidosis; chronic kidney disease; chronic metabolic acidosis; complement.

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References

    1. DuBose TD: Disorders of acid-base balance. In: Brenner and Rector’s The Kidney, 10th Ed., edited by Skorecki K, Chertow GM, Marsden PA, Taal MW, Yu ASL, Philadelphia, Elsevier, 2016, pp 511–558
    1. Nath KA, Hostetter MK, Hostetter TH: Pathophysiology of chronic tubule-interstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3. J Clin Invest 76: 667–675, 1985 - PMC - PubMed
    1. Codina J, Opyd TS, Powell ZB, Furdui CM, Petrovic S, Penn RB, DuBose Jr. TD: pH-dependent regulation of the α-subunit of the H+-K+-ATPase (HKα2). Am J Physiol Renal Physiol 301: F536–F543, 2011 - PMC - PubMed
    1. Dong L, Krewson EA, Yang LV: Acidosis activates endoplasmic reticulum stress pathways through GPR4 in human vascular endothelial cells. Int J Mol Sci 18: 278–292, 2017 - PMC - PubMed
    1. Justus CR, Sanderlin EJ, Yang LV: Molecular connections between cancer cell metabolism and the tumor microenvironment. Int J Mol Sci 16: 11055–11086, 2015 - PMC - PubMed

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