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Comparative Study
. 1985;81(4):935-8.
doi: 10.1016/0300-9629(85)90933-8.

Changes in the macrophage function with aging

M De La Fuente
Comparative Study

Changes in the macrophage function with aging

M De La Fuente. Comp Biochem Physiol A Comp Physiol. 1985.

Abstract

Changes in the adherence, opsonization, phagocytosis, nitroblue tetrazolium reduction and antibody-dependent cell cytotoxicity of peritoneal macrophages were observed with aging in BALB/C mice. A decrease in all the parameters studied, except for the reduction capacity of nitroblue tetrazolium, which increased with aging, was found in the long-lived mice. The role of the macrophage in immune hyporesponsiveness with aging is discussed.

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