Partners in Crime
- PMID: 28633011
- DOI: 10.1016/j.devcel.2017.06.002
Partners in Crime
Abstract
Caspases have apoptotic and non-apoptotic functions, both of which depend on their abilities to cleave proteins at specific sites. What distinguishes apoptotic from non-apoptotic substrates has so far been unclear. In this issue of Developmental Cell, Weaver et al. (2017) now provide an answer to this crucial question.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development.Dev Cell. 2017 Jun 19;41(6):665-673.e6. doi: 10.1016/j.devcel.2017.05.013. Epub 2017 Jun 8. Dev Cell. 2017. PMID: 28602583 Free PMC article.
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