Liver transplantation for hepatocellular carcinoma

Abstract

Over the last several years, liver transplantation has evolved to become a widely used treatment for hepatocellular carcinoma (HCC). The criteria used were developed in order to have acceptable outcomes for transplant with survival similar to other indications for transplant. These criteria are discussed in detail along with alternate options, including surgical resection and downstaging of HCC in cirrhotics. Technical considerations of liver transplantation must be considered, and living donor liver transplant is a possibility for treatment.

Keywords: Bridging therapy; Hepatocellular carcinoma; Liver transplant; Living donor liver; Milan criteria.