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Comment
. 2017 Jun 20;46(6):979-981.
doi: 10.1016/j.immuni.2017.06.011.

T-Regulating Hair Follicle Stem Cells

Maria Maryanovich  1 , Paul S Frenette  2
Affiliations
Free article
Comment

T-Regulating Hair Follicle Stem Cells

Maria Maryanovich et al. Immunity. .
Free article

Abstract

Regulatory T (Treg) cells are well known to modulate inflammatory responses. In a recent issue of Cell, Ali et al. (2017) reveal a function for Treg cells in stem cell maintenance by showing that skin-resident Foxp3+ Treg cells preferentially localize to the hair follicle stem cell (HFSC) niche to control HFSC-mediated hair regeneration.

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  • Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.
    Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, Cotsarelis G, Abbas AK, Rosenblum MD. Ali N, et al. Cell. 2017 Jun 1;169(6):1119-1129.e11. doi: 10.1016/j.cell.2017.05.002. Epub 2017 May 25. Cell. 2017. PMID: 28552347 Free PMC article.

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