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Review
. 2017 Jun;4(2):161-165.
doi: 10.5152/eurjrheum.2017.16006. Epub 2017 Apr 11.

Pre-rheumatoid arthritis and its prevention

Binoy J Paul  1 , Hemanth Illath Kandy  1 , Vinod Krishnan  1
Affiliations
Review

Pre-rheumatoid arthritis and its prevention

Binoy J Paul et al. Eur J Rheumatol. 2017 Jun.

Abstract

Pre-rheumatoid arthritis (pre-RA) is the preclinical period of the disease that precedes the onset of clinically apparent RA. It includes the interaction between genetic and environmental risk factors and development of disease-related autoantibodies and joint symptoms and signs, which may be considered nonspecific or unclassified for RA. A better understanding of the pre-RA stage will be useful in developing screening programs for early detection of RA. Identifying and modifying risk factors such as smoking, periodontitis, obesity, viral infections, and hormonal or dietary factors will be useful in preventing RA in susceptible population.

Keywords: Pre-rheumatoid arthritis; rheumatoid arthritis prevention; unclassified arthritis.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
Phases of pre-rheumatoid arthritis
Figure 2
Figure 2
Environmental risk factors for rheumatoid arthritis
Figure 3
Figure 3
Fate of undifferentiated arthritis
Figure 4
Figure 4
Leiden prediction rule
See this image and copyright information in PMC

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