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. 2017 Mar;6(1):260.
doi: 10.4172/2167-0277.1000260. Epub 2017 Mar 10.

Obesity, Cardiovascular Disease and Sleep Disorders: Insights into the Rising Epidemic

Navneet Sharma  1 , Justin Lee  1 , Irini Youssef  1 , Moro O Salifu  1 , Samy I McFarlane  1
Affiliations

Obesity, Cardiovascular Disease and Sleep Disorders: Insights into the Rising Epidemic

Navneet Sharma et al. J Sleep Disord Ther. 2017 Mar.

Abstract

Cardiovascular disease (CVD) is the main cause of death among adult men and women in the USA and impacts millions around the globe. Traditional risk factors for CVD include obesity, diabetes, hypertension and dyslipidemia. The modern-day epidemic of obesity not only increased the rate of CVD but also ushered in an additional CVD risk factor to be added to the list; that is obstructive sleep apnea (OSA). In this review, we discuss the growing epidemic of obesity and OSA, highlighting the common pathogenic hypotheses linking these risk factors to CVD. We will also highlight the therapeutic rationale of OSA as a way to reduce CVD risk.

Keywords: Cardiovascular disease; Obesity; Sleep disorders.

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Figures

Figure 1
Figure 1
Interrelation between obesity, obstructive sleep apnea, and cardiovascular disease.
Figure 2
Figure 2
Pathophysiology of Obstructive sleep apnea leading to cardiovascular disease.
Figure 3
Figure 3
Progression of Obstructive Sleep Apnea to Cardiovascular Disease with potential treatments to inhibit or slow the progression from Obstructive Sleep Apnea to Cardiovascular Disease.
See this image and copyright information in PMC

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