Economic Barriers in the Treatment of Clostridium difficile Infection With Oral Vancomycin
- PMID: 28638841
- PMCID: PMC5472230
- DOI: 10.1093/ofid/ofx078
Economic Barriers in the Treatment of Clostridium difficile Infection With Oral Vancomycin
Abstract
Vancomycin is an increasingly important option for the treatment of Clostridium difficile infection, but economic barriers to its use remain significant in the outpatient setting. Generic vancomycin capsules are still inexplicably expensive and not universally covered by insurers. This report highlights the potential adverse consequences of cost-related nonadherence to vancomycin therapy and the challenges that clinicians face when prescribing oral vancomycin.
Keywords: Clostridium difficile; pharmaceutical costs; vancomycin..
References
-
- Johnson S, Louie TJ, Gerding DN et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials. Clin Infect Dis 2014; 59:345–54. - PubMed
-
- Walker PC, Nagel J. Clostridium difficile relapse secondary to medication access issue AHRQ WebM&M; [serial online]. Available at: https://psnet.ahrq.gov/webmm/case/321/clostridium-difficile-relapse-seco... Published April 2014. Accessed September 25, 2016.
-
- Kesselheim AS, Avorn J, Sarpatwari A. The high cost of prescription drugs in the United States: origins and prospects for reform. JAMA 2016; 316:858–71. - PubMed
-
- Alpern JD, Stauffer WM, Kesselheim AS. High-cost generic drugs–implications for patients and policymakers. N Engl J Med 2014; 371:1859–62. - PubMed
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