Lipodystrophy: Time for a global registry and randomized clinical trials to assess efficacy, safety and cost-effectiveness of established and novel medications

Affiliations

¹ First Department of Pharmacology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: stergios@endo.gr.
² Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Editorial

Stergios A Polyzos et al. Metabolism. 2017 Jul.

. 2017 Jul:72:A4-A10.

doi: 10.1016/j.metabol.2017.06.003.

¹ First Department of Pharmacology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: stergios@endo.gr.
² Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

No abstract available

Keywords: adipokine; adipose tissue; familial partial lipodystrophy; leptin; lipodystrophy; metreleptin.

Comment on

Role of PARL-PINK1-Parkin pathway in adipocyte differentiation.
Shiau MY, Lee PS, Huang YJ, Yang CP, Hsiao CW, Chang KY, Chen HW, Chang YH. Shiau MY, et al. Metabolism. 2017 Jul;72:1-17. doi: 10.1016/j.metabol.2017.03.010. Epub 2017 Mar 30. Metabolism. 2017. PMID: 28641777
Clinical presentations, metabolic abnormalities and end-organ complications in patients with familial partial lipodystrophy.
Akinci B, Onay H, Demir T, Savas-Erdeve Ş, Gen R, Simsir IY, Keskin FE, Erturk MS, Uzum AK, Yaylali GF, Ozdemir NK, Atik T, Ozen S, Yurekli BS, Apaydin T, Altay C, Akinci G, Demir L, Comlekci A, Secil M, Oral EA. Akinci B, et al. Metabolism. 2017 Jul;72:109-119. doi: 10.1016/j.metabol.2017.04.010. Epub 2017 Apr 27. Metabolism. 2017. PMID: 28641778