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Case Reports
. 2017 Jun 23:2017:bcr2017220416.
doi: 10.1136/bcr-2017-220416.

Obesity-related hypogonadism: a reversible condition

Stamatios Zouras  1 , Jeffrey W Stephens  2 , David Price  1
Affiliations
Case Reports

Obesity-related hypogonadism: a reversible condition

Stamatios Zouras et al. BMJ Case Rep. .

Abstract

Obesity is associated with hypogonadism. While this association is widely accepted, the underlying mechanisms remain unclear. Furthermore, obesity is a risk factor for hypogonadism and conversely hypogonadism may be a risk factor for obesity. We present the case of a morbidly obese man aged 30 years with hypogonadotrophic hypogonadism that underwent a Roux-en-Y gastric bypass operation. Following the surgical treatment of his obesity, the testosterone level returned to normal with improvements in hypogonadal symptoms, which allowed discontinuation of exogenous testosterone therapy. This case report demonstrates reversal of hypogonadism following weight loss with restoration of gonadal function.

Keywords: Endocrine system; Gastrointestinal surgery; Metabolic disorders; Obesity (nutrition); Pituitary disorders.

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Conflict of interest statement

Competing interests: None declared.

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