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. 2017 Jul;92(1):6-8.
doi: 10.1016/j.kint.2017.05.001.

Gastric bypass surgery stimulates the dormant gut-brain axis in obesity

Stephanie P B Caligiuri  1 , Paul J Kenny  2
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Gastric bypass surgery stimulates the dormant gut-brain axis in obesity

Stephanie P B Caligiuri et al. Kidney Int. 2017 Jul.
Free article

Abstract

To truly reduce the rates of chronic kidney disease, a root cause of kidney damage, obesity, must be targeted. Weight loss is often unsustainable because imbalances in satiety regulators are frequently not addressed to ensure maintenance of weight loss. In a recent study, gastric bypass surgery rebalanced satiety signals through resensitization of the gut-brain axis in obesity. This research may lead to noninvasive strategies to reduce obesity and obesity-related kidney disease.

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