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. 2018 Feb;31(1):95-102.
doi: 10.1007/s40620-017-0417-7. Epub 2017 Jun 24.

A questionnaire survey of radiological diagnosis and management of renal dysplasia in children

Giovanni Montini  1 , Marco Busutti  2 , Fatos Yalcinkaya  3 , Adrian S Woolf  4 , Stefanie Weber  5 ; European Society for Paediatric Nephrology Working Group on Congenital Anomalies of the Kidney and Urinary Tract
Collaborators, Affiliations

A questionnaire survey of radiological diagnosis and management of renal dysplasia in children

Giovanni Montini et al. J Nephrol. 2018 Feb.

Abstract

Background: The condition called renal dysplasia is considered to be a frequent cause of chronic kidney disease in children. Formally, it is defined by histological parameters. In current nephrology practice, however, the appearance of the kidneys on ultrasound scanning is often used as a basis for the diagnosis.

Methods: The European Society for Pediatric Nephrology Working Group on Congenital Anomalies of the Kidney and Urinary Tract hypothesized that the current diagnostic approach with regard to renal dysplasia was not homogeneous. Accordingly, we here report the results of a survey targeting pediatric nephrologists with 12 questions regarding their perceptions of the ultrasonographic characteristics of renal dysplasia and further tests that they might undertake.

Results: Of almost 1200 physicians who successfully received the invitation, 248 from 54 countries completed the survey. There was a notable lack of homogeneity regarding the ultrasonographic diagnosis of renal dysplasia and also of follow-up tests, including genetic testing and further radiology.

Conclusions: Based on the responses to this large survey, a picture emerges of nephrologists' current clinical practice with regard to renal dysplasia. The Working Group considers that these results serve as an important sounding board which can provide the basis for more definitive recommendations regarding the challenges to clinical diagnosis and diagnostic follow-up of this important condition.

Keywords: CAKUT; Children; Chronic kidney disease; Genetic testing; Renal dysplasia; Ultrasonography.

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Conflict of interest statement

Funding

GM acknowledges grant support from the Italian Ministry of Health and the Foundations Il Sogno di Stefano and the Nando Peretti Foundation. ASW acknowledges grant support from the Medical Research Council MR/L002744/1 and RENALTRACT Horizons Marie Sklodowska-Curie Actions Initial Training Network 642937.

Conflict of interest

The authors declare that they have no conflict of interest.

Research involving human participants or animals

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

For this type of study formal consent is not required.

Figures

Fig. 1
Fig. 1
Definition of renal dysplasia
Fig. 2
Fig. 2
Imaging of renal dysplasia
Fig. 3
Fig. 3
Genetics of renal dysplasia
Fig. 4
Fig. 4
Genetics of renal dysplasia
See this image and copyright information in PMC

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