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. 2016 Sep 2;6(9):6207-6213.
doi: 10.1021/acscatal.6b01886. Epub 2016 Aug 17.

Iridium-Catalyzed Diastereo-, Enantio-, and Regioselective Allylic Alkylation with Prochiral Enolates

J Caleb Hethcox  1 , Samantha E Shockley  1 , Brian M Stoltz  1
Affiliations

Iridium-Catalyzed Diastereo-, Enantio-, and Regioselective Allylic Alkylation with Prochiral Enolates

J Caleb Hethcox et al. ACS Catal. .
No abstract available

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Conflict of interest statement

Notes The authors declare no competing financial interest.

Figures

Figure 1
Figure 1
Metallacyclic iridium catalysts.
Scheme 1
Scheme 1
Transition-Metal-Catalyzed Asymmetric Allylic Alkylation
Scheme 2
Scheme 2
Iridium-Catalyzed Asymmetric Allylic Alkylation
Scheme 3
Scheme 3
First Report of Diastereo- and Enantioselective Iridium-Catalyzed Allylic Alkylation
Scheme 4
Scheme 4
Allylic Alkylation of Acyclic β-Ketoesters by Stoltz
Scheme 5
Scheme 5
Allylic Alkylation with Acyclic α-Alkoxy Ketones by Hartwig
Scheme 6
Scheme 6
Counterion-Assisted Iridium-Catalyzed Allylic Alkylation of Azlactones by Hartwig
Scheme 7
Scheme 7
Cation Control of Diastereoselectivity in Iridium-Catalyzed Allylic Alkylation of (a) 5H-Oxazol-4-ones 21 and (b) 5H-Thiazol-4-ones 25 by Hartwig
Scheme 8
Scheme 8
Allylic Alkylation of (a) Bicyclic β-Ketoesters 28 and (b) Monocyclic β-Ketoesters 31 by Stoltz
Scheme 9
Scheme 9
Allylic Alkylation of Extended Enolates by Stoltz
Scheme 10
Scheme 10
Allylic Alkylation of Non-Stabilized Enolates by Hartwig
Scheme 11
Scheme 11
Dual-Catalyst-Promoted Allylic Alkylation of Aldehydes by Carreira
Scheme 12
Scheme 12
Proline-Derived Dual Catalysis by Carreira
Scheme 13
Scheme 13
Diastereoablative Allylic Alkylation of 52 by Stoltz
See this image and copyright information in PMC

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