Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jan;32(2):189-194.
doi: 10.1080/14786419.2017.1344660. Epub 2017 Jun 26.

Two new protostane-type triterpenoids from Alisma orientalis

Xiu-Lan Xin  1   2 , Xin-Yu Zhao  2   3 , Xiao-Kui Huo  2 , Xiang-Ge Tian  4 , Cheng-Peng Sun  2 , Hou-Li Zhang  2 , Yan Tian  2 , Yong Liu  3 , Xun Wang  5
Affiliations

Two new protostane-type triterpenoids from Alisma orientalis

Xiu-Lan Xin et al. Nat Prod Res. 2018 Jan.

Abstract

Two new protostane-type triterpenoids, 17-epi alisolide (1) and 24-epi alismanol D (2), were isolated from Alisma orientalis together with one known compound. Their structural elucidations were conducted by NMR, UV and HRESIMS spectroscopic analyses, and comparison with the literature data. All the isolated compounds were evaluated for inhibitory effects on HCE-2. Compound 2 displayed moderate inhibitory activity against HCE-2 with IC50 value of 23.1 μM.

Keywords: Alisma orientalis; HCE-2; protostane-type triterpenoid.

PubMed Disclaimer

MeSH terms