Fulminant Sepsis Due to Granulibacter bethesdensis in a 4-Year-Old Boy With X-Linked Chronic Granulomatous Disease
- PMID: 28650935
- PMCID: PMC5897898
- DOI: 10.1097/INF.0000000000001659
Fulminant Sepsis Due to Granulibacter bethesdensis in a 4-Year-Old Boy With X-Linked Chronic Granulomatous Disease
Abstract
Granulibacter bethesdensis is a Gram-negative bacillus described as a pathogen exclusively in patients with chronic granulomatous disease, a phagocytic disorder that impairs the ability to clear catalase-producing organisms. Granulibacter usually causes chronic and recurrent lymphadenopathies. We report the fatal case of a 4-year-old boy with chronic granulomatous disease, who presented with sepsis after a few days of abdominal pain and diarrhea.
Conflict of interest statement
The authors have no funding or conflicts of interest to disclose.
References
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- NIH. [Accessed May 25, 2017];Chronic Granulomatous Disease National Institute of Health—U.S. National Library of Medicine. 2016 Available at: https://ghr.nlm.nih.gov/condition/chronic-granulomatous-disease.
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- López FC, de Luna FF, Delgado MC, et al. Granulibacter bethesdensis isolated in a child patient with chronic granulomatous disease. J Infect. 2008;57:275–277. - PubMed
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