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. 2017 Jun 8:10:181-188.
doi: 10.2147/IMCRJ.S125972. eCollection 2017.

Optic perineuritis: a retrospective case series

Olle Bergman  1 , Tommy Andersson  1 , Madeleine Zetterberg  1   2
Affiliations

Optic perineuritis: a retrospective case series

Olle Bergman et al. Int Med Case Rep J. .

Abstract

Optic perineuritis (OPN) is a rare inflammatory disorder involving the optic nerve sheath characterized by visual loss. OPN may be isolated and idiopathic or part of an underlying disorder. This case series aimed to help clinicians investigate and manage this disorder. Presentation, clinical findings, and treatment of OPN are discussed. After review of medical records at the ophthalmology clinic at Sahlgrenska University hospital in Gothenburg, Sweden, seven OPN patients (three men and four women) were identified and included in the present case series. These included idiopathic cases and patients with underlying disorders. Age at OPN diagnosis ranged from 26 to 64 years (mean age 55 years, median age 58 years). Five of the patients were treated with corticosteroids. This study suggests that a high-dose course of corticosteroids is important in the treatment of OPN in severely affected patients.

Keywords: corticosteroids; glucocorticoids; idiopathic; inflammation; magnetic resonance imaging; prednisone; vision.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Coronal post-contrast T1 fat-saturated magnetic resonance imaging of Patient 7 demonstrating circumferential enhancement in the left optic nerve sheath.
Figure 2
Figure 2
Axial post-contrast T1 fat-saturated magnetic resonance imaging of Patient 7 showing enhancement in the left optic nerve sheath from the eye to the chiasma.
Figure 3
Figure 3
Fundus photo of Patient 7 1 month after first examination, showing an optic disc edema.
See this image and copyright information in PMC

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