Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Sep;23(9):1607-1609.
doi: 10.3201/eid2309.170915. Epub 2017 Sep 17.

A New Bat-HKU2-like Coronavirus in Swine, China, 2017

Lang Gong, Jie Li, Qingfeng Zhou, Zhichao Xu, Li Chen, Yun Zhang, Chunyi Xue, Zhifen Wen, Yongchang Cao

A New Bat-HKU2-like Coronavirus in Swine, China, 2017

Lang Gong et al. Emerg Infect Dis. 2017 Sep.

Abstract

We identified from suckling piglets with diarrhea in China a new bat-HKU2-like porcine coronavirus (porcine enteric alphacoronavirus). The GDS04 strain of this coronavirus shares high aa identities (>90%) with the reported bat-HKU2 strains in Coronaviridae-wide conserved domains, suggesting that the GDS04 strain belongs to the same species as HKU2.

Keywords: China; Coronaviridae; PEAV; bat-HKU2; coronavirus; diarrhea; porcine enteric alphacoronavirus; swine; viruses; zoonoses.

PubMed Disclaimer

Figures

Figure
Figure
Phylogenetic tree based on the whole-genome sequences of PEAV, bat CoVs, and other representative CoVs, China, 2017. Analyses were conducted by using MEGA software version 6.0 (http://www.megasoftware.net) with the neighbor-joining algorithm. Bootstrap values were calculated with 1,000 replicates. The number on each branch indicates bootstrap values. Solid triangle indicates the GDS04 strain, open triangles alphacoronaviruses, circles betacoronavirusese, squares gammacoronaviruss, inverted triangle deltacoronavirus. Scale bar indicates nucleotide substitutions per site. CoV, coronavirus; PDCoV, porcine deltacoronavirus; PEAV, porcine enteric alphacoronavirus; PEDV, porcine epidemic diarrhea virus; PHEV, porcine hemagglutinating encephalomyelitis virus; PRCV, porcine respiratory coronavirus; SARS, severe acute respiratory syndrome; TGEV, transmissible gastroenteritis virus.
See this image and copyright information in PMC

References

    1. Sun RQ, Cai RJ, Chen YQ, Liang PS, Chen DK, Song CX. Outbreak of porcine epidemic diarrhea in suckling piglets, China. Emerg Infect Dis. 2012;18:161–3. 10.3201/eid1801.111259 - DOI - PMC - PubMed
    1. Pensaert MB, de Bouck P. A new coronavirus-like particle associated with diarrhea in swine. Arch Virol. 1978;58:243–7. 10.1007/BF01317606 - DOI - PMC - PubMed
    1. Dong N, Fang L, Zeng S, Sun Q, Chen H, Xiao S. Porcine deltacoronavirus in mainland China. Emerg Infect Dis. 2015;21:2254–5. 10.3201/eid2112.150283 - DOI - PMC - PubMed
    1. Theuns S, Vyt P, Desmarets LM, Roukaerts ID, Heylen E, Zeller M, et al. Presence and characterization of pig group A and C rotaviruses in feces of Belgian diarrheic suckling piglets. Virus Res. 2016;213:172–83. 10.1016/j.virusres.2015.12.004 - DOI - PubMed
    1. Reuter G, Boros A, Pankovics P. Kobuviruses - a comprehensive review. Rev Med Virol. 2011;21:32–41. 10.1002/rmv.677 - DOI - PubMed

LinkOut - more resources