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. 2008 Apr;1(2):112-116.
doi: 10.1093/ndtplus/sfn006. Epub 2008 Feb 14.

Tubulointerstitial nephritis and uveitis (TINU) syndrome: epidemiology, diagnosis and management

Kim T Sinnamon  1 , Aisling E Courtney  2 , Camille Harron  1 , Declan M O'Rourke  3 , Robert N Mullan  1
Affiliations

Tubulointerstitial nephritis and uveitis (TINU) syndrome: epidemiology, diagnosis and management

Kim T Sinnamon et al. NDT Plus. 2008 Apr.
No abstract available

Keywords: corticosteroids; tubulointerstitial nephritis; uveitis.

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Figures

Fig. 1
Fig. 1
Renal biopsy specimen showing widespread interstitial inflammation with a predominant mononuclear cell infiltrate (haematoxylin and eosin stain).
Fig. 2
Fig. 2
Improvement in renal function from time of diagnosis. Oral corticosteroid dose was tapered from 60 mg daily to zero by 44 weeks.
Fig. 3
Fig. 3
Graph with superimposed trend lines representing the ongoing improvement in renal function (eGFR was calculated by the four-variable MDRD equation) in three cases of TINU (represented by three differing symbols) over a prolonged period of time. This improvement continued after withdrawal of oral corticosteroids (mean corticosteroid duration = 19 weeks; range 17–23 weeks).
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