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Review
. 2017 Sep;55(9):2590-2598.
doi: 10.1128/JCM.00582-17. Epub 2017 Jun 28.

Reliable Detection of Group B Streptococcus in the Clinical Laboratory

Manuel Rosa-Fraile  1 , Barbara Spellerberg  2
Affiliations
Review

Reliable Detection of Group B Streptococcus in the Clinical Laboratory

Manuel Rosa-Fraile et al. J Clin Microbiol. 2017 Sep.

Abstract

Group B streptococcus (GBS) is a leading cause of invasive neonatal infections and a significant pathogen in immunocompromised adults. Screening to detect GBS colonization in pregnant women determines the need for antibiotic prophylaxis in that pregnancy. Efficient determination of the GBS colonization status of pregnant women is crucial. Methods that maximize the probability of GBS recovery are needed. The availability of technologies such as matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), molecular techniques, and chromogenic culture media, including Granada-type media, have changed the scenario for GBS detection and identification. This review presents and evaluates novel diagnostic tools, as well as classic identification techniques, for GBS species determination.

Keywords: GBS; group B streptococcus.

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References

    1. Edwards MS, Nizet V, Baker CJ. 2016. Group B streptococcal infections, p 411–456. In Wilson CB, Nizet V, Maldonado Y, Klein JO, Remington JS (ed), Remington and Klein's infectious diseases of the fetus and newborn infant. Elsevier Saunders, Philadelphia, PA.
    1. Fry RM. 1938. Fatal infections by hemolytic streptococcus group B. Lancet i:199–201.
    1. Hood M, Janney A, Dameron G. 1961. Beta hemolytic streptococcus group B associated with problems of the perinatal period. Am J Obstet Gynecol 82:809–818. doi:10.1016/S0002-9378(16)36146-4. - DOI - PubMed
    1. Verani JR, McGee L, Schrag SJ. 2010. Prevention of perinatal group B streptococcal disease–revised guidelines from CDC. MMWR Recomm Rep 59(RR-10):1–36. - PubMed
    1. Edwards MS, Baker CJ. 2005. Group B streptococcal infections in elderly adults. Clin Infect Dis 41:839–847. doi:10.1086/432804. - DOI - PubMed

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