Strengthening brittle bones
- PMID: 28659442
- DOI: 10.1126/scitranslmed.aan6730
Strengthening brittle bones
Abstract
Decreased WNT1 signaling weakens bones but is partially reversed by blocking the WNT1 inhibitory regulator sclerostin.
Copyright © 2017, American Association for the Advancement of Science.
Comment on
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Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis.J Clin Invest. 2017 Jun 30;127(7):2678-2688. doi: 10.1172/JCI92617. Epub 2017 Jun 19. J Clin Invest. 2017. PMID: 28628032 Free PMC article.
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