Structure of the murine Thy-1 gene
- PMID: 2866091
- PMCID: PMC554456
- DOI: 10.1002/j.1460-2075.1985.tb03886.x
Structure of the murine Thy-1 gene
Abstract
We have cloned the murine Thy-1.1 (AKR) and Thy-1.2 (Balb/c) genes. The complete exon/intron structure and the nucleotide sequence of the Thy-1.2 gene was determined. The gene contains four exons and three intervening sequences. The complete transcriptional unit gives rise to a tissue and developmental stage-specific mRNA of 1850 bp. The 5' end of the gene has multiple initiation sites and a non-TATA box promoter. The 3' end shows a single polyadenylation site after a very long untranslated region.
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