Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Published Erratum
. 2017 Jun 29;9(1):61.
doi: 10.1186/s13073-017-0451-z.

Erratum to: Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson's disease patients

J R Bedarf  1   2 , F Hildebrand  3 , L P Coelho  3 , S Sunagawa  3   4 , M Bahram  5   6 , F Goeser  7   8 , P Bork  9   10   11   12   13 , U Wüllner  14   15   16
Affiliations
Published Erratum

Erratum to: Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson's disease patients

J R Bedarf et al. Genome Med. .
No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Genus and species level differences in PD participants and controls. a NMDS ordination of all samples used in this study, using a Bray–Curtis between-sample distance at genus level. This shows the composition relatedness of samples and that PD samples form a subgroup. Outliers denoted with # took antibiotics in a period of 28–34 days prior to feces sampling. See also Additional file 2 for taxonomic analysis while taking these samples into account. b Genus-level sample composition. c The most significant species or groups of taxa that could not be further classified. Unclassified Prevotella is not significant after multiple testing, but was implied in PD in several studies (see “Discussion”). d Species correlating strongest to PD disease severity (as measured by UPDRS III). Note that after multiple testing correction, these are all q > 0.1
Fig. 4
Fig. 4
Structural equation modeling (SEM). SEM analysis of PD in relation to key correlating bacterial functions and taxa (MSEA = 0, PCLOSE = 0.79, AIC = 59.385). Values on paths and boxes are standardized regression and determination coefficients (R2), respectively. Dashed lines and red colors denote negative relationships. The thickness of lines is proportional to regression coefficients. All relationships are statistically significant (P < 0.05, Additional file 5). AIC Akaike information criterion, MSEA mean square error of approximation, PCLOSE probability of close fit
See this image and copyright information in PMC

Erratum for

References

    1. Bedarf JR, et al. Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients. Genome Medicine. 2017;9:39. doi: 10.1186/s13073-017-0428-y. - DOI - PMC - PubMed

Publication types