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Review
. 2017 Aug;58(8):1196-1200.
doi: 10.2967/jnumed.117.191023. Epub 2017 Jun 29.

177Lu-PSMA Radioligand Therapy for Prostate Cancer

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Free article
Review

177Lu-PSMA Radioligand Therapy for Prostate Cancer

Wolfgang P Fendler et al. J Nucl Med. 2017 Aug.
Free article

Erratum in

  • Errata.
    [No authors listed] [No authors listed] J Nucl Med. 2018 Feb;59(2):346. J Nucl Med. 2018. PMID: 29419456 No abstract available.

Abstract

177Lu-prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) using inhibitors of PSMA is a novel therapeutic option in patients with metastatic castration-resistant prostate cancer. The current literature suggests that this therapy is well tolerated and effective. On the basis of clinical need and current evidence, the therapy is being implemented in a growing number of centers worldwide. Here, we review important aspects of 177Lu-PSMA RLT, including patient stratification, the therapy protocol, concomitant medication, and follow-up, to inform medical staff involved in the RLT and care of patients with metastatic castration-resistant prostate cancer.

Keywords: PSMA; education; genitourinary; lutetium; radionuclide therapy; therapy.

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