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. 2017 Jun 9:17:20-24.
doi: 10.1016/j.mmcr.2017.06.002. eCollection 2017 Sep.

Disseminated Nannizziopsis obscura infection in a renal transplant patient- The first reported case

Affiliations

Disseminated Nannizziopsis obscura infection in a renal transplant patient- The first reported case

Amy Baggott et al. Med Mycol Case Rep. .

Abstract

This is a presentation of a case of disseminated fungal infection in a renal transplant patient with Nannizziopsis obscura, a species not previously reported as having caused disseminated disease in humans and not previously reported in the UK. The fungus was isolated from a intramuscular collection and from a lymph node. The patient responded well to a course of posaconazole.

Keywords: Nannizziopsis; Renal transplant.

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Figures

Fig. 1
Fig. 1
Anterior view of truncal rash.
Fig. 2
Fig. 2
Posterior view of truncal rash; dressing at site of thoracic collection drainage.
Fig. 3
Fig. 3
Plantar lesions, right foot.
Fig. 4
Fig. 4
Truncal rash, detail.
Fig. 5
Fig. 5
Phylogenetic tree containing patient isolate sequence (generated from the CBS database) .
Fig. 6
Fig. 6
Colonies of Nannizziopsis sp. on Sabouraud agar.
Fig. 7
Fig. 7
Lactophenol cotton blue staining of Nannizziopsis culture.
Fig. 8
Fig. 8
Microscopy of Nannizziopsis culture showing arthroconidia in chains.
Fig. 9
Fig. 9
X100 Fluorescence microscopy of calcofluor stained tissue.

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References

    1. White T.J., Bruns T., Lee S.J.W.T., Taylor J.W. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. PCR Protoc.: a Guide Methods Appl. 1990;18(1):315–322.
    1. Seifert K., Morgan-Jones G., Gams W., Kendrick B. Centraalbureau voor Schimmelcultures; Utrecht, The Netherlands: 2011. The Genera of Hyphomycetes.
    1. Pare J.A., Sigler L., Hunter D.B., Summerbell R.C., Smith D.A., Machin K.L. Cutaneous mycoses in chameleons caused by the Chrysosporium anamorph of Nannizziopsis vriesii (Apinis) Currah. J. Zoo Wildl. Med.: Off. Publ. Am. Assoc. Zoo. Vet. 1997;28(4):443–453. - PubMed
    1. Nichols D.K., Weyant R.S., Lamirande E.W., Sigler L., Mason R.T. Fatal mycotic dermatitis in captive brown tree snakes (Boiga irregularis) J. Zoo Wildl. Med.: Off. Publ. Am. Assoc. Zoo. Vet. 1999;30(1):111–118. - PubMed
    1. Thomas A.D., Sigler L., Peucker S., Norton J.H., Nielan A. Chrysosporium anamorph of Nannizziopsis vriesii associated with fatal cutaneous mycoses in the saltwater crocodile (Crocodylus porosus) Med. Mycol. 2002;40(2):143–151. - PubMed

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