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Review
. 2017 Oct;35(10):937-953.
doi: 10.1016/j.tibtech.2017.06.002. Epub 2017 Jun 27.

Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology

Mohammad Javad Hajipour  1 , Michelle R Santoso  2 , Farhad Rezaee  3 , Haniyeh Aghaverdi  4 , Morteza Mahmoudi  5 , George Perry  6
Affiliations
Review

Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology

Mohammad Javad Hajipour et al. Trends Biotechnol. 2017 Oct.

Abstract

Alzheimer's disease (AD) is a type of dementia that causes major issues for patients' memory, thinking, and behavior. Despite efforts to advance AD diagnostic and therapeutic tools, AD remains incurable due to its complex and multifactorial nature and lack of effective diagnostics/therapeutics. Nanoparticles (NPs) have demonstrated the potential to overcome the challenges and limitations associated with traditional diagnostics/therapeutics. Nanotechnology is now offering new tools and insights to advance our understanding of AD and eventually may offer new hope to AD patients. Here, we review the key roles of nanotechnologies in the recent literature, in both diagnostic and therapeutic aspects of AD, and discuss how these achievements may improve patient prognosis and quality of life.

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