Endometrial receptivity in eutopic endometrium in patients with endometriosis: it is not affected, and let me show you why

Abstract

Many women with endometriosis experience compromised fertility. This disease clearly exerts quantitative damage on the ovaries, and perhaps, also qualitative damage. However, it remains controversial whether endometrial receptivity is compromised. Here we review the evidence from basic transcriptomic signature data to clinical data from an oocyte donation model and find support for the concept that endometrial receptivity is not impaired in women with endometriosis when healthy embryos reach the endometrial cavity.

Keywords: Endometrial receptivity; array; transcriptomic signature.