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Case Reports
. 2017 Jul 3;11(1):179.
doi: 10.1186/s13256-017-1352-x.

Possible gasoline-induced chronic liver injury due to occupational malpractice in a motor mechanic: a case report

Affiliations
Case Reports

Possible gasoline-induced chronic liver injury due to occupational malpractice in a motor mechanic: a case report

Mahesh Lakmal Gunathilaka et al. J Med Case Rep. .

Abstract

Background: Hydrocarbon-induced occupational liver injury is a well-known clinical entity among petroleum industry workers. There are many types of hydrocarbon exposure, with inhalation being the most common. Hydrocarbon-induced occupational liver injury is a rarely suspected and commonly missed etiological agent for liver injury. We report a case of a non-petroleum industry worker with chronic liver disease secondary to hydrocarbon-induced occupational liver injury caused by chronic low-grade hydrocarbon ingestion due to occupational malpractice.

Case presentation: A 23-year-old Sri Lankan man who was a motor mechanic presented to our hospital with decompensated cirrhosis. He had been chronically exposed to gasoline via inadvertent ingestion due to occupational malpractice. He used to remove gasoline from carburetors by sucking and failed to practice mouth washing thereafter. On evaluation, he had histologically proven established cirrhosis. A comprehensive history and workup ruled out other nonoccupational etiologies for cirrhosis. The patient's long-term occupational gasoline exposure and clinical course led us to a diagnosis of hydrocarbon-induced occupational liver injury leading to decompensated cirrhosis.

Conclusions: Hydrocarbon-induced occupational liver injury should be considered as a cause when evaluating a patient with liver injury with possible exposure in relevant occupations.

Keywords: Case report; Chronic liver injury; Cirrhosis; Gasoline; Hydrocarbon; Occupational liver injury.

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Figures

Fig. 1
Fig. 1
Liver biopsy showing features of cirrhosis (hematoxylin and eosin stain, original magnification ×40)

References

    1. Mowry JB, Spyker DA, Cantilena LR, Jr, McMillan N, Ford M. 2013 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 31st annual report. Clin Toxicol (Phila) 2014;52(10):1032–283. doi: 10.3109/15563650.2014.987397. - DOI - PMC - PubMed
    1. Seymour FK, Henry JA. Assessment and management of acute poisoning by petroleum products. Hum Exp Toxicol. 2001;20(11):551–62. doi: 10.1191/096032701718620918. - DOI - PubMed
    1. Palmer RB, Phillips SD. Chlorinated hydrocarbons. In: Shannon MW, Borron SW, Burns MJ, editors. Haddad and Winchester’s clinical management of poisoning and drug overdose. 4. Philadelphia: Saunders Elsevier; 2007. pp. 1347–61.
    1. Malaguarnera G, Cataudella E, Giordano M, Nunnari G, Chisari G, Malaguarnera M. Toxic hepatitis in occupational exposure to solvents. World J Gastroenterol. 2012;18(22):2756–66. doi: 10.3748/wjg.v18.i22.2756. - DOI - PMC - PubMed
    1. Døssing M. Occupational toxic liver damage. J Hepatol. 1986;3(1):131–5. doi: 10.1016/S0168-8278(86)80157-X. - DOI - PubMed

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